Research Areas:
Education:

1996 University of South Carolina, South Carolina Honors College B.S.

2003 University of Delaware Ph.D.

National Institutes of Health, Ruth L. Kirschstein National Research Service Award (NRSA) Postdoctoral Fellowship, University of Michigan, 2005

Hoppers A, Stoudenmire J, Wu S, Lopanik NB. 2015. Antibiotic activity and microbial community of the temperate sponge, Haliclona sp. Journal of Applied Microbiology 118:413-430.

Linneman J, Paulus D, Lim-Fong G, Lopanik NB. 2014. Latitudinal Variation of a Defensive Symbiosis in the Bugula neritina (Bryozoa) Sibling Species Complex. PLoS One 9:e108783.

Mathew M, Lopanik NB. 2014. Host Differentially Expressed Genes during Association with its Defensive Endosymbiont. Biological Bulletin 226:125-163.

   Editor’s Pick.

Lopanik NB. 2014. Chemical defensive symbioses in the marine environment.

Functional Ecology 28:328-340.

Parsley LC, Linneman J, Goode AM, Becklund K, George I, Goodman RM, Lopanik NB, Liles MR. 2011. Polyketide synthase pathways identified from a metagenomic library are derived from soil Acidobacteria. FEMS Microbiology Ecology. 78:176-187.

Buchholz TJ, Rath CM, Lopanik NB, Gardner NP, Hakansson K, Sherman DH. 2010.

Polyketide β-Branching in Bryostatin Biosynthesis: Identification of Surrogate Acetyl-ACP Donors for BryR, an HMG-ACP Synthase. Chemistry & Biology 17:1092-1100.

Lopanik NB, Shields JA, Buchholz TJ, Rath CM, Hothersall J, Haygood MG, Hakansson K, Thomas CM, Sherman DH. 2008. In vivo and in vitro trans-acylation by BryP, the putative bryostatin pathway acyltransferase derived from an uncultured marine symbiont. Chemistry & Biology 15:1175-1186.

Cover figure.

Sudek S, Lopanik NB, Waggoner LE, Hildebrand M, Anderson C, Liu HB, Patel A, Sherman DH, Haygood MG. 2007. Identification of the putative bryostatin polyketide synthase gene cluster from "Candidatus Endobugula sertula", the uncultivated microbial symbiont of the marine bryozoan Bugula neritina.

Journal of Natural Products 70:67-74.

Sitachitta N, Lopanik NB, Mao Y, Sherman DH. 2007. Analysis of a parallel branch in the mitomycin biosynthetic pathway involving the mitN-encoded aziridine N-methyltransferase. Journal of Biological Chemistry.

282:20941-20947.

Lopanik NB, Targett NM, Lindquist N. 2006. Isolation of two polyketide synthase gene fragments from the uncultured microbial symbiont of the marine bryozoan Bugula neritina. Applied and Environmental Microbiology 72:7941-7944.

Lopanik NB, Targett NM, Lindquist N. 2006. Ontogeny of a symbiont-produced chemical defense in Bugula neritina (Bryozoa). Marine Ecology Progress Series. 327:183-191.

Lopanik N, Lindquist N, Targett N. 2004. Potent cytotoxins produced by a microbial symbiont protect host larvae from predation. Oecologia 139:131-139.

Lopanik N, Gustafson KR, Lindquist N. 2004. Structure of bryostatin 20: A symbiont-produced chemical defense for larvae of the host bryozoan, Bugula neritina. Journal of Natural Products 67:1412-1414.